Prevention of Variceal Bleeding and Rebleeding by Nonselective Beta-Blockers
نویسندگان
چکیده
منابع مشابه
Cost-effectiveness analysis of variceal ligation vs. beta-blockers for primary prevention of variceal bleeding.
Although both beta-blockade (BB) and endoscopic variceal ligation (EVL) are used for primary prevention of variceal bleeding (VB) in patients with cirrhosis with moderate to large esophageal varices (EVs), the more cost-effective option is uncertain. We created a Markov decision model to compare BB and EVL in such patients, examining both cost-effectiveness (cost per life year [LY]) and cost-ut...
متن کاملPrevention of variceal rebleeding.
CONTEXT Variceal bleeding is the most frequent severe complication of portal hypertension and a leading cause of death and liver transplantation in patients with cirrhosis. Patients surviving a variceal bleed are at high risk of rebleeding (over 60% at 1 year). Portacaval shunts and transjugular intrahepatic portasystemic shunts (TIPS) are effective for prevention of rebleeding but carry a high...
متن کاملPrevention of esophageal variceal rebleeding.
The rate of rebleeding of esophageal varices remains high after cessation of acute esophageal variceal hemorrhage. Many measures have been developed to prevent the occurrence of rebleeding. When considering their effectiveness in reduction of rebleeding, the associated complications cannot be neglected. Due to unavoidable high incidence of complications, shunt surgery and endoscopic injection s...
متن کاملReview article: the modern management of portal hypertension--primary and secondary prophylaxis of variceal bleeding in cirrhotic patients.
BACKGROUND Variceal bleeding is a life-threatening complication of liver cirrhosis with a high probability of recurrence. Treatment to prevent first bleeding or rebleeding is mandatory. AIM To provide an overview of the current knowledge on the best evidence-based therapeutic options to prevent first or recurrent bleeding from oesophageal varices in patients with cirrhosis. METHODS For the ...
متن کاملPrevention of recurrent variceal bleeding.
Patients surviving a first episode of variceal bleeding have a risk of over 60% of experiencing recurrent haemorrhages within 1 year from the index episode. Because of this, all patients surviving a variceal bleeding should receive active treatments for the prevention of rebleeding. beta-Blockers+/-isosorbide-5-mononitrate and band ligation are effective in preventing recurrent bleeding and bot...
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ژورنال
عنوان ژورنال: Clinics in Liver Disease
سال: 2021
ISSN: 1089-3261
DOI: 10.1016/j.cld.2021.01.004